Acthar is a prescription medicine to be used as a short-term, add-on therapy in the event of symptoms suddenly worsening (flare) for rheumatoid arthritis, including juvenile rheumatoid arthritis. Some cases may require maintenance therapy.

What Is RA?

Rheumatoid arthritis (RA) is a common disease that causes:

  • Inflammation
  • Pain
  • Swelling
  • Damage in your joints

RA can also cause damage to important organs, such as your heart.

RA affects nearly 3 times as many women as men.

What causes RA?

RA is an autoimmune disease. This means your body’s immune system attacks bone and tissues in your joints. It can cause pain, stiffness, and joint damage. This can make your usual daily activities hard.

What are flares?

The symptoms of RA are chronic, meaning that they continue over time. There can be sudden increases in symptoms, called flares. Keeping your symptoms as low as possible can help prevent damage to your joints and organs.

Common RA symptoms

  • Tender, warm, swollen joints
  • Morning stiffness that may last for hours
  • Firm bumps of tissue under the skin on your arms (rheumatoid nodules)
  • Pain and fatigue

A chronic condition that can have periods of worsening symptoms

RA is a chronic condition. This means you need to manage it for the rest of your life. RA causes pain, stiffness, and swelling of the joints. All of these symptoms are caused by inflammation.

Some people with RA may have periods when their disease gets worse. This can happen even with ongoing treatment. This may lead to some added pain and discomfort. It is unclear why these periods occur. But when they do, additional treatment may be needed.

Acthar is a prescription medication that can be used as an add-on to your current RA treatment. It may be used over a short period. In some cases, your doctor may prescribe it as maintenance therapy. Acthar may help if you experience sudden worsening of RA symptoms. Talk to your doctor to find out if Acthar may be an option for you.


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DO NOT take Acthar until you have talked to your doctor if you have any of the following conditions:

  • A skin condition called scleroderma
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